Major cities or major attractions in the Sacred Valley include:
Other destinations near to or accessible from cities in the Sacred Valley include:
;Cuzco: Although most of the Inca buildings have been replaced by the Spaniards, there are still some Inca walls and foundations to be seen in the center of Cuzco.
;Sacsayhuaman: Cuzco was envisioned to represent a puma with Sacsayhuaman as head. Large parts of the site has been destroyed in the colonial era as the spainards used the stones of the sites to build their own houses. What remains is still impressive. Admission with ''boleto turistico''.
;Qenqo: This site is hewn out of a rock. It probably served as religious shrine. Admission with ''boleto turistico''.
;Pucapucara: A small site. Which purpose it served is still unclear. Admission with ''boleto turistico''.
;Tambomachay: A small ruin which probably was a religious center, but could also be a military center. Walk back and visit ''pucapucara'', ''qenqo'' en ''sacsayhuaman'' on the way back. Admission with ''boleto turistico'' (See Cuzco).
;Pisac: The mountain overlooking the village of Pisac is covered with terraces and several ruins. Well worth a visit. Admission with ''boleto turistico''.
;Moray (Peru): Amphitheater shaped terraces. It probably served as an agricultural laboratory and seed cultivation site.
;Tipon: A group of agricultural terraces and irrigation channels. It is believed to be dedicated to agricultural experimentation as well as religious activities. Admission with ''boleto turistico''.
;Ollantaytambo: In the town of Ollantaytambo houses can be seen which date from Inca times. The nearby ruins features agricultural terraces as well as military, religious and administrative sections. Admission to the ruins with ''boleto turistico''.
;Choquequirao:According to some this site is as impressive as Machu Picchu, but without the crowds. The only way in is a 4 day trek.
;Machu Picchu: The star attraction of the sacred valley. Also the endpoint of the Inca Trail
;Pikillacta: One of the few pre-Inca sites. It has been built by the Wari-culture. Admission with ''boleto turistico''.